Inducible mouse transgenic lines

Mouse lines using inducible genetic technology referenced in Breunig JJ, Arellano JI, Macklis JD, Rakic P. Everything that Glitters Isn't Gold: A Critical Review of Postnatal Neural Precursor Analyses. Cell Stem Cell 2007 Dec 13;1:612-627. PMID: 18371403.

Name Promoter Type Reference
Tamoxifen Inducible
Ascl1-CreERâ„¢ BAC containing Ascl1 genomic Cre-ERT1 Battiste et al. 2007
GCE huGFAP Cre-ERT2 Ganat et al. 2006
GFAP-CreERT2 huGFAP Cre-ERT2 Hirrlinger et al. 2006
GLAST::CreERT2 Knockin to endogenous GLAST locus Cre-ERT2 Mori et al. 2006
Gli1-CreERT2 Knockin to the endogenous Gli1 locus Cre-ERT2 Ahn and Joyner 2005
Nestin-CreER Nestin 2nd intron/Hsp68 minimal Cre-ERT1 Burns et al. 2007
Nestin-CreERT2 Xh5 plasmid
(large fragment including Nestin promoter/instrons/e xons)
Cre-ERT2 Battiste et al. 2007
Nes-CreER(T2) Nestin/Nestin 2nd intron Cre-ERT2 Imayoshi et al. 2006
Nestin-Cre-ERT2 Nestin 2nd intron/Hsp68 minimal Cre-ERT2 Carlen et al. 2006
Nestin-creERtm Nestin Promoter and 2nd intron Cre-ERT1 Kuo et al. 2006
Ngn2-CreERâ„¢ Knockin to endogenous Ngn2 locus Cre-ERT1 Raineteau et al. 2006
Tetracycline Regulated
Nestin-rtTA-M2 Nestin/Nestin 2nd intron rtTA-M2 Yu et al. 2005
Nestin-tTA Xh5 plasmid (see above) tTA Beech et al. 2005